Skin redness can occur for several reasons. A small percentage of tretinoin users experience some degree of redness after using tretinoin, typically during the first few days of applying the cream, gel or solution to the face. Redness of the skin is the most common side effect of topical tretinoin. During this period, your skin is more likely to feel irritated and peel as the tretinoin gets to work preventing acne. Many of these side effects are most common during the first two to six weeks of tretinoin use-a period many users refer to as the tretinoin “purge” or adjustment period. The most common side effects of tretinoin gel, cream and solution are skin redness, abnormal skin peeling and increased sensitivity to sunlight. Most users experience few or no side effects, with studies of tretinoin skin treatments noting that the cream and gel forms of tretinoin have a “low incidence of reported adverse effects.” The trick is learning how to use tretinoin cream properly and effectively while mitigating these potential side effects. On the whole, topical tretinoin is an extremely safe medication with few side effects. It does not include side effects for oral tretinoin, which is typically not used to treat acne or as an anti-aging treatment.īelow, we’ve listed both the common side effects of tretinoin use that you may experience while under treatment, and the medication’s less common potential side effects you should be aware of. Our list of tretinoin side effects below focuses on the topical form of tretinoin used to treat acne and the physical effects of aging. Tretinoin is also manufactured as an oral medicine for use as a treatment for acute promyelocytic leukemia. This form of the medication is intended for use as an anti-aging and acne treatment. Tretinoin is most commonly sold as a topical cream, gel or solution. However, as with all medications, there are several potential side effects of tretinoin that you should be aware of before using the gel, cream or solution. As one of the most widely used topical retinoids, tretinoin has a great safety record.
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